Moderna Says Coronavirus Vaccine's Effectiveness Will Likely Hold Against New SARS-CoV-2 Variants
Moderna Inc (NASDAQ: MRNA) has assured that there is nothing to worry as the world is threatened by the prospect of SARS-CoV-2 mutating to produce new virulent strains.
What happened: The vaccine-induced immunity to Moderna's coronavirus vaccine candidate - mRNA-1273 - is likely to protect against the new strain of SARS-CoV-2 recently described in the UK, the Massachusetts-based company said in a Declaration from late Wednesday with.
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The company based the deduction on previous data.
Tests of sera from animals and humans vaccinated with mRNA-1273 have been performed against a number of previous variants of SARS-CoV-2, and the vaccine has remained equally effective.
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"The full-length spike protein is 1,273 amino acids long. While newer variants contain several mutations, for example up to 8 amino acid changes in the spike protein of the B1.1.7 strain, these represent less than 1% difference to the spike protein, which is encoded by Moderna's vaccine, "the company stated.
What's next? Moderna plans to run tests to confirm the vaccine's activity against each strain.
The broad spectrum of potential neutralizing antibodies made possible by mRNA-1273 gives confidence that it will also effectively induce neutralizing antibodies against them.
Moderna's vaccine candidate approval from the FDA on December 18, and most recently Health Canada under an interim injunction to vaccinate people aged 18 and over.
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