Oxford Researchers Identify First Drug Proven to Reduce COVID Fatalities

Oxford University researchers announced on Tuesday that after a clinical trial of dexamethasone, a low-cost steroid treatment, they had found the first proven life-saving coronavirus treatment that reduced the risk of death for coronavirus patients with ventilators and by a third a fifth for those who have oxygen.
The study, which is part of the UK's Recovery Trial project to identify existing treatments for COVID-19, compared approximately 2,000 hospitalized patients who received dexamethasone to almost 4,000 patients who did not receive the drug.
In patients with ventilators, the risk of death was reduced from 40 to 28 percent, while in patients who needed oxygen, the risk of death was reduced from 25 to 20 percent.
Rhys Blakely

@ Rhysblakely
Break: Oxford researchers find the first drug has been shown to reduce deaths from Covid

The inexpensive steroid dexamethasone reduced death in ventilated patients by a third

At the start of the pandemic, it could have saved some 5,000 lives in the UK

It costs about £ 5 - about £ 40 saves a life
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“This is the only drug that has been shown to reduce mortality and significantly reduce it. This is a big breakthrough, ”said Dr. Peter Horby, chief investigator of the study, made a statement. The lead researcher Dr. Martin Landray added that the low cost of the drug would make it even more effective.
“There is a clear, clear advantage. Treatment lasts up to 10 days of dexamethasone and costs around GBP 5 per patient. So it essentially costs £ 35 to save a life. This is a drug that is available worldwide, ”he said, stressing that one life could be saved for eight patients with ventilators treated with the drug.
The only other drug that is promising in a clinical setting for the treatment of coronavirus is Remdesivir, an experimental antiviral treatment that has shown promise in treating patients at the start of the infection.
Oxford researchers have also made significant progress with a vaccine following positive studies with rhesus monkeys that were healthy after 28 days, despite being exposed to large amounts of coronavirus, which made the control group sick.
Oxford University researcher John Bell, who leads the project, said in May that the vaccine's ability to "generate strong antibody responses will likely be fine," but the verdict on whether it is a safe treatment would be still unclear.
"We are pretty sure we will get a signal by June whether this will work or not," said Bell.
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